Drug & Alcohol Rehab Centers in South Carolina
Discover 92 addiction treatment facilities in South Carolina. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.
Need assistance locating an ideal treatment program?
Reach out now - completely at no cost!
Call +1 (888) 555-0199
24/7 Support
Thousands of Centers
Showing 20 of 92 results
+9 photos
Columbia, SC 29201
803-733-5855
Crossroads Treatment Centers in Columbia, SC provides comprehensive detoxification and substance use disorder treatment with specialized support for pregnant and postpartum women. Their outpatient programs include medication-assisted treatment with methadone, buprenorphine, and naltrexone, complemented by evidence-based counseling and telehealth therapy options. CARF-accredited and SAMHSA-certified as an opioid treatment program, Crossroads combines clinical expertise with compassionate care for recovery.
DetoxificationSubstance use treatment
+9 photos
Faith Home Inc
Christian Alcohol/Drug Rehabilitation
Greenwood, SC 29649
864-223-0694
Faith Home Inc in Greenwood, SC provides comprehensive long-term residential substance use treatment grounded in 12-step facilitation and evidence-based recovery strategies. Their state-accredited program combines relapse prevention counseling with specialized substance use disorder treatment in a 24-hour residential setting designed for sustained healing and community support.
Substance use treatment
+8 photos
Lancaster, SC 29720
803-285-6911
Counseling Services of Lancaster provides comprehensive substance use treatment in Lancaster, SC, specializing in evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. The facility serves adolescents and forensic clients through flexible outpatient and intensive outpatient programs, including medication-assisted treatment options. Accredited by CARF and state agencies, they focus on sustainable recovery through relapse prevention and individualized counseling.
Substance use treatment
+8 photos
Crossroads Treatment Centers
Greenville PC
Greenville, SC 29615
864-288-7636
Crossroads Treatment Centers in Greenville, SC provides comprehensive substance use disorder treatment with specialized support for pregnant and postpartum women. The center offers evidence-based detoxification, medication-assisted treatment (methadone, buprenorphine, naltrexone), and counseling through both in-person and telehealth options. As a SAMHSA-certified opioid treatment program, Crossroads combines flexible outpatient care with professional clinical expertise to support sustainable recovery.
DetoxificationSubstance use treatment
+7 photos
Clinton, SC 29325
864-547-2089
Clear Skye Treatment Center in Clinton, SC specializes in comprehensive substance use disorder treatment through evidence-based outpatient programs, including medication-assisted therapy with methadone, buprenorphine, and naltrexone. The center employs a diverse range of therapeutic approaches—from cognitive behavioral therapy and motivational interviewing to trauma-informed counseling and anger management—tailored to individual recovery needs. With CARF accreditation and SAMHSA certification as an opioid treatment program, Clear Skye delivers clinically rigorous care in a supportive outpatient setting.
Substance use treatment
+7 photos
Gaffney, SC 29341
800-792-9030
Clear Skye Treatment Center in Gaffney, SC specializes in substance use disorder treatment through evidence-based relapse prevention and counseling. The center offers flexible outpatient care, including medication-assisted treatment with methadone, buprenorphine, and naltrexone, plus telehealth therapy options. Clear Skye serves diverse populations including military members, LGBTQ individuals, pregnant women, and seniors with compassionate, inclusive programming.
Substance use treatment
+7 photos
Crossroads Treatment Centers
Charleston
Charleston, SC 29406
843-207-4721
Crossroads Treatment Centers in Charleston, SC specializes in comprehensive substance use disorder treatment with a particular focus on supporting pregnant and postpartum women. The facility offers evidence-based approaches including the Matrix Model and medication-assisted treatment (methadone, buprenorphine, naltrexone) through flexible outpatient and telehealth options. Multiple accreditations from CARF, DEA, SAMHSA, and state health authorities demonstrate their commitment to clinical excellence and safety.
Substance use treatment
+5 photos
Seneca, SC 29678
864-888-2337
Crossroads Treatment Centers in Seneca, SC specializes in comprehensive substance use disorder treatment with a particular focus on supporting pregnant and postpartum women. The facility offers detoxification, medication-assisted treatment (methadone, buprenorphine, naltrexone), and evidence-based counseling through flexible outpatient settings and telehealth options. CARF and SAMHSA-certified, Crossroads combines clinical expertise with compassionate care designed for individuals at every stage of recovery.
DetoxificationSubstance use treatment
+4 photos
Cornerstone
Greenwood
Greenwood, SC 29649
864-227-1001
Cornerstone in Greenwood, SC specializes in comprehensive substance use treatment with integrated mental health and trauma care for adolescents and adults. The facility offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling, with flexible delivery through in-person intensive outpatient and telemedicine options. CARF-accredited and state-licensed, Cornerstone serves individuals with co-occurring disorders, including those managing pain and substance use together.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
+4 photos
Dorchester County Commission on
Alcohol and Drug Abuse
Summerville, SC 29485
843-871-4790
Dorchester County Commission on Substance Use in Summerville, SC provides comprehensive addiction and co-occurring mental health treatment for adolescents, adults, and young adults. Specializing in both intensive outpatient and medication-assisted treatment programs, this accredited facility serves trauma survivors, domestic violence victims, and criminal justice-involved individuals with evidence-based therapies including CBT, motivational interviewing, and relapse prevention. Their integrated approach addresses substance use disorders alongside serious mental illness, ensuring whole-person recovery.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
+3 photos
Circle Park Behavioral Health Services
Florence Cnty Commission on AODA
Florence, SC 29501
843-665-9349
Circle Park Behavioral Health Services in Florence, SC specializes in comprehensive substance use disorder treatment with evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and relapse prevention. The facility serves diverse populations—from active duty military and veterans to pregnant women and LGBTQ individuals—with specialized programs addressing trauma, co-occurring mental health conditions, and pain management. Their flexible care model includes intensive outpatient and medication-assisted treatment options, with telemedicine access for added convenience.
Substance use treatment
+2 photos
Winnsboro, SC 29180
803-635-2335 x19
Fairfield Behavioral Health Services in Winnsboro, SC specializes in comprehensive substance use treatment with evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. The facility serves adolescents and adults with co-occurring mental health and substance use disorders, offering flexible outpatient options and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their integrated approach to anger management, relapse prevention, and telemedicine access makes treatment accessible and personalized for each client's needs.
Substance use treatment
+1 photos
Clarendon Cty Commission on Alc Trt
DBA Clarendon Behavioral Health Servs
Manning, SC 29102
803-435-2121
Clarendon County Commission on Alcohol Treatment in Manning, SC provides comprehensive outpatient substance use disorder treatment with a focus on evidence-based therapies and trauma-informed care. The facility specializes in serving diverse populations including adolescents, adults, and individuals involved in the criminal justice system, utilizing cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. Their telemedicine capabilities ensure accessible care for clients managing co-occurring mental health and substance use challenges.
Substance use treatment
Myrtle Beach, SC 29577
843-449-6261
Coastal Recovery and Wellness in Myrtle Beach, SC offers comprehensive substance use treatment and detoxification services for adults and children with co-occurring mental health conditions. The facility provides flexible outpatient care, including intensive day treatment, medication-assisted therapy (methadone, buprenorphine, naltrexone), and evidence-based counseling approaches. Accredited by The Joint Commission and state health departments, Coastal Recovery combines clinical expertise with personalized treatment planning for lasting recovery.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cornerstone
McCormick
Mc Cormick, SC 29835
864-852-3306
Cornerstone in McCormick, SC specializes in comprehensive substance use treatment and co-occurring disorder care for adults and children. Their evidence-based programs address trauma, pain management alongside addiction, and criminal justice-involved populations through intensive and regular outpatient settings. Accredited by CARF and state agencies, Cornerstone combines proven therapies like cognitive behavioral therapy, motivational interviewing, and relapse prevention with convenient telehealth options.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cornerstone
Abbeville
Abbeville, SC 29620
864-366-9661
Cornerstone in Abbeville, SC specializes in comprehensive substance use treatment and co-occurring disorder care for adults and children. The facility employs evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling through both in-person and telehealth options. CARF accreditation ensures quality care for individuals navigating dual diagnoses of mental health and substance use challenges.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Goose Creek, SC 29445
843-797-7871
Ernest E Kennedy Center in Goose Creek, SC specializes in comprehensive substance use treatment for adolescents, young adults, and LGBTQ individuals. The center employs evidence-based approaches including cognitive behavioral therapy, trauma-focused counseling, and relapse prevention strategies, with flexible delivery through both in-person and telehealth options. Accredited by CARF and state regulatory bodies, the facility combines intensive outpatient and regular outpatient programs with integrated anger management support.
Substance use treatment
Colleton County Commission on Alcohol
DBA Colleton Pillars4Hope
Walterboro, SC 29488
843-538-4343
Colleton County Commission on Alcohol in Walterboro provides comprehensive substance use treatment through evidence-based outpatient and intensive programs tailored to diverse populations. Serving everyone from adolescents to seniors, the facility specializes in trauma-informed care for clients with complex needs, including those experiencing domestic violence, sexual abuse, and co-occurring mental health or pain disorders. CARF-accredited and state-regulated, they combine proven therapeutic approaches like cognitive behavioral therapy, motivational interviewing, and relapse prevention with telehealth options for accessible recovery support.
Substance use treatment
Cornerstone
Edgefield
Edgefield, SC 29824
803-637-9336
Cornerstone is an accredited substance use and co-occurring mental health treatment facility in Edgefield, SC, serving adolescents and adults with complex needs including trauma and chronic pain. The center offers intensive and standard outpatient programs utilizing evidence-based therapies like cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling. Their specialized approach addresses the interconnected challenges of addiction, mental illness, and pain management, with flexible telemedicine options for ongoing care.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Moncks Corner, SC 29461
843-761-8272
Ernest E Kennedy Center in Moncks Corner, SC provides comprehensive substance use treatment with specialized care for diverse populations including pregnant women, trauma survivors, and those with co-occurring disorders. The center offers evidence-based approaches such as cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling through both in-person and telehealth formats. Accredited by CARF and state agencies, it delivers intensive outpatient and medication-assisted treatment options tailored to individual recovery needs.
Substance use treatment
Latest Recovery Resources
Types of Rehabilitation Programs and How to Choose the Right One
Explore different rehabilitation program types and learn how to select the best fit for your unique recovery needs and circumstances.
RehabilitationTreatment ProgramsRecovery Options
Jessica Martinez
March 17, 2026
6 min read
Supporting a Loved One Through the Recovery Process
Learn how to provide meaningful support to someone in addiction recovery with practical strategies and compassionate guidance.
Family SupportRecoveryRelationships
Robert Thompson
March 17, 2026
6 min read
FeaturedRecognizing Signs of Addiction and When to Seek Help
Learn to identify warning signs of addiction and discover when it's time to reach out for professional support.
RecoveryTreatmentAddiction Signs
Dr. Michael Chen
March 17, 2026
5 min read
Addiction Treatment in South Carolina
South Carolina offers a comprehensive network of addiction treatment facilities to help individuals overcome substance abuse and mental health challenges. From luxury rehabilitation centers to state-funded programs, you'll find options that match your needs and budget.
Types of Treatment Available
- • Detox Centers: Medical supervision for safe withdrawal from substances
- • Residential Treatment: 24/7 care in a structured environment
- • Outpatient Programs: Flexible treatment while maintaining daily responsibilities
- • Sober Living Homes: Transitional housing for ongoing recovery support
- • Dual Diagnosis: Integrated treatment for addiction and mental health
Insurance and Payment Options
Most rehabilitation centers in South Carolina accept major insurance plans including Medicaid, Medicare, and private insurance. Many facilities also offer sliding scale fees, payment plans, and scholarships to ensure treatment is accessible to everyone who needs it.